Diagnosis and Management of Primary Tracheobronchial Non-Hodgkin lymphoma (NHL): A Rare Case
Tasneem Bohra
Department of Respiratory Medicine, Lilavati Hospital and Research Center, Mumbai, India.
K. V. Charan Reddy *
Department of Cardiology, Lilavati Hospital and Research Center, Mumbai, India.
B. K. Smruti
Department of Medical Oncology, Lilavati Hospital and Research Center, Mumbai, India.
Prahlad Prabhudesai
Department of Respiratory Medicine, Lilavati Hospital and Research Center, Mumbai, India.
*Author to whom correspondence should be addressed.
Abstract
Tracheobronchial Non-Hodgkin Lymphoma (NHL) is a rare tumor with very few cases reported in medical literature. These tumors typically present as endobronchial mass and/or mucosal infiltration together with lymphadenopathy. They are often misdiagnosed as asthma or chronic obstructive pulmonary disease. Involvement of central airway can cause respiratory failure making treatment difficult, leading to poor prognosis. Histopathological examination is often necessary for definitive diagnosis. These tumors have been a topic of interest due to the challenge they pose to early diagnosis and management Here, we report a uncommon case of primary tracheobronchial NHL and complications encountered during management. This case illustrates that NHL should also be considered as a differential diagnosis in patient who present with central airway obstruction.
Keywords: Tracheobronchial neoplasm, non-hodgkin lymphoma, central airway obstruction.
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References
Wang AY, Wang JT, Shen Y, Levin B. Relapse of non-Hodgkin’s lymphoma involving the trachea: Acute subglottic obstruction. Case Reports in Otolaryngo-logy. 2014;230682.
Chand T, Bansal A, Dua H, Sharma K. Endotracheobronchial lymphoma: Two unusual case reports and review of article. Lung India: Official organ of Indian Chest Society. 2016;33:653-56.
Yang FF, Gao R, Miao Y, Yan XJ, Hou G, Li Y, Wang QY, Kang J. Primary trachea-bronchial non-Hodgkin lymphoma causing life-threatening airway obstruction: A case report. Journal of Thoracic Disease. 2015; 7:E667.
Takami A, Okumura H, Maeda Y, Kumano Y, Asakura H, Oda M, et al. Primary tracheal lymphoma: Case report and literature review. Int J Hematol. 2005;82: 338-42.
Velez Jo ET, Morehead RS. Hemoptysis and dyspnea in a 67-year-old man with a normal chest radiograph. Chest. 1999; 116:803-7.
Gasparetto TD, Azevedo FB, Toledo A, Zanetti G, Marchiori E. Primary tracheal non-Hodgkin lymphoma: Case report with an emphasis on computed tomography findings. J Thorac Imaging. 2010;25:W24-26.
Fernandez FG, Denlinger CE, Crabtree TD. Primary non-Hodgkin's lymphoma of the trachea. Journal of Thoracic 1. Oncology. 2010;5:403-04.